Agree with everything you said. All true. I had many of the same thoughts as you concerning axial loads. But I recently changed my mind concerning those loads.
I suspect that the differences in axial loads are not as great as one might think they are. Certainly if you are comparing a TB 110 mm and an Iwonder wheel turning a corner on a perfectly flat and smooth surface then the TB wants to sit flat and the Iwonder wants to twist. Agreed. Totally.
However once the surface becomes irregular and bumpy then the reverse happens. The square profile TB tire hits a rock on the outside edge and then it wants to twist because the entire weight is sitting on the outside edge. Its a shock load with a great deal of leverage against the centerline of the tire.
The soft and round profile Iwonder would absorb the irregularity of the rock. The shock load would be less sever. The further the rock hits from the centerline of the iwonder tire, the less sever the shock and the lighter the load.
I’m not saying the Iwonder tire is superior. I’m just saying that when you move from a hardwood floor to a rough road, it becomes difficult to argue that the Iwonder core has more sever twists and loads to deal with compared to a conventional large diameter PU wheel.
What the Iwonder does suffer from is an insufficient quantiy of core material and a problematic un-reinforced core composition.
A conventional Nylon +GF core configured for Kegle might have enough structure to support the bearing without cracking. I can’t see the spokes cracking. I don’t think the rim would collapse.
I’d say Iwonder should atlease test a prototype. Lathe the core out of a traditional PU wheel, shape it like an Iwonder Rim. Bond an Iwonder tire to it as a rough prototype for stress testing.