It’s no concrete solution but here are some basics to go over.
Sometimes it takes disconnecting and turning off and on and trying again to work properly. That was the case with my V1 Ubox over Bluetooth, and my v2.1 completely didnt have an internal can connection until I updated firmware to 6.05. I believe there is a setting for enable / disable can bus but it is very likely on already.
If you have this one it uses a cable instead of an internal can bus thing. Also check that there isn’t a physical switch accessible through the top for the can bus like my lower voltage Ubox has.
If nothing works you could always plug into each side separately or use 2 Bluetooth modules for changing settings, is it just changing settings where you have this issue or does it not work properly?